Ariessence PDGF+: The Next Evolution in Under-Eye Rejuvenation

If you’ve been with me at Wild & Beautiful for a while, you know I’m obsessed with finding the best, most effective treatments to keep your skin looking incredible.

I don’t jump on every trend—if it’s not backed by science and doesn’t deliver real, noticeable results, it’s not making its way into our treatment menu.

That’s why I’ve been a huge fan of PRF (platelet-rich fibrin) for under-eye rejuvenation. It harnesses your body’s own healing power to restore volume, smooth texture, and improve skin quality.

Before and After 3 Treatments of PRF Under Eye Injections

Before and After 3 Treatments of PRF Under Eye Injections

But as amazing as PRF is, there’s always been one challenge: it depends entirely on you. Some days your PRF is rich with growth factors and works like magic. Other days—because of hydration levels, stress, or even how well you slept—it’s just not as strong.

This is where PDGF+ from Ariessence changes the game. I’m talking about a 1,000+ times more potent treatment that’s scientifically proven to stimulate collagen, elastin, and hyaluronic acid production at levels we’ve never seen before. This isn’t just an upgrade—it’s a whole new way to approach under-eye rejuvenation.

Why I’m So Excited About PDGF+

I’ll be honest—when I first heard about PDGF+, I thought, Okay, but how much better can it really be? But after diving into the research, I was impressed.

  • PDGF (Platelet-Derived Growth Factor) is the most powerful collagen stimulator we’ve ever had access to in aesthetics. It’s backed by clinical studies and has four FDA approvals—not just for skincare, but for wound healing, dentistry, and orthopedic treatments. It’s been used successfully in medical fields for over 15 years.

  • It’s not dependent on your blood quality. Unlike PRF, which varies from person to person (and even from day to day), PDGF+ is recombinantly manufactured, meaning every dose is sterile, consistent, and maximally potent.

  • It contains just four ingredients—Water, Sodium Acetate, Hyaluronic Acid, and the active ingredient Sh-polypeptide-59 dimer (aka the powerhouse protein responsible for insane tissue regeneration). No unnecessary fillers, no human-to-human transfer—just pure, concentrated skin rejuvenation.

  • It’s 1,000-300,000 times more potent than PRP/PRF. Yes, you read that right. Imagine multiplying the effects of PRF by over a thousand. That’s what we’re working with here.

How PDGF+ Works & Why It’s Perfect for Under Eyes

Under-eye hollowness, darkness, and thinning skin are some of the hardest things to treat in aesthetics. Fillers? They can work, but they’re not for everyone (and they don’t actually improve skin quality). Lasers? Great for texture, but they don’t add back volume. PRF? A solid choice, but unpredictable.

PDGF+ is different. Here’s why:

  1. Collagen & Elastin Stimulation – PDGF+ activates your skin’s fibroblasts, the little factories responsible for producing collagen and elastin. The result? Thicker, stronger, more resilient under-eye skin.

  2. Hyaluronic Acid Production – This isn’t filler—it’s your skin making its own HA, leading to natural hydration, plumpness, and that dewy, youthful glow.

  3. Tissue Regeneration & Repair – Because PDGF+ is FDA-approved for wound healing in other medical spaces, it has an unmatched ability to repair and restore delicate, aging skin.

  4. No Variability – It’s 100% consistent, every single time. No worrying about hydration levels, diet, or lifestyle factors impacting your results.

PDGF+ Under Eyes

Courtesy of @dontage_va; Before & After One PDGF+ Under Eye Injection

How We’re Using PDGF+ at Wild & Beautiful

While PDGF+ can be used for microneedling and full-face rejuvenation, I’m most excited about using it for under-eye treatments.

  • For patients who already love PRF, this is your next-level upgrade.

  • For those hesitant about PRF because of blood draws or inconsistent results, PDGF+ is the answer.

  • For anyone wanting a powerful, natural, and science-backed solution for under-eye aging, this is it.

PDGF+ is also excellent as a post Erbium Yag laser serum to maximize results and significantly reduce downtime.

Final Thoughts: Is This Worth the Hype?

I get it—every new treatment sounds like it’s the best thing ever. But here’s the thing: I’ve built Wild & Beautiful on real results, not gimmicks. I wouldn’t bring in PDGF+ unless I believed it was a true game-changer.

And this? This is a game-changer.

If you’re curious, let’s talk. I’ll always be honest about what’s best for your skin, and if PDGF+ is the right fit, I can’t wait for you to experience it.

See you soon,


Jen

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